New Orleans Center for Clinical Research
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CURRICULUM VITAE

WILLIAM B. SMITH, M.D., F.A.C.C.

 

OFFICE:          New Orleans Center for Clinical Research
                         2820 Canal Street
                         New Orleans, Louisiana    70119
                         (504) 821-8158

                         Canal Street Cardiology Associates
                         2820 Canal Street
                         New Orleans, LA  70119
                         (504) 821-8158          

PERSONAL:    Born June 16, 1949, Memphis, Tennessee; US citizen

EDUCATION:

B.S. University of Tennessee, 1970

M.D. Universidad Autonoma de Guadalajara, 1974

 POST GRADUATE

12/74-12/75           Clinical Clerk, Internal Medicine, Hahneman Medical School, Philadelphia, Pennsylvania

1/1/76-12/31/76     Intern, Internal Medicine, University of Tennessee, Knoxville, Tennessee

 1/1/77-7/31/78      Resident, Internal Medicine, University of Tennessee, Knoxville, Tennessee

7/1/78-6/30/80       Fellow, Nephrology Fellowship, Vanderbilt University, Nashville, Tennessee

7/1/80-6/30/82       Fellow, Cardiology Fellowship, Tulane University Medical Center Affiliated Hospitals, New Orleans, Louisiana

CERTIFICATIONS AND EXAMINATIONS

Internal Medicine, 1981; Nephrology, 1982; Cardiovascular Disease,  1983;   Critical Care Medicine, 1987; ECFMG, 1974; FLEX 1976

LICENSURE

State of Tennessee, 1976;

State of Louisiana, 1980;

APPOINTMENTS

ACADEMIC:

Instructor, Internal Medicine and Nephrology, Tulane University School of Medicine, 1980-1982

Assistant Professor of Medicine, Tulane University School of Medicine, 1982-1984

Assistant Professor, Clinical Medicine, Tulane University School of Medicine,   1984-1989

Associate Professor, Clinical Medicine, Tulane University School of Medicine, 1989-Present

Associate Professor, Clinical Medicine, Louisiana State University Medical Center, 1990-Present

HOSPITAL:

Visiting Staff, Cardiology and Nephrology, Claiborne County Hospital,  Tazewell, Tennessee, 1980-1985

Visiting Staff, Cardiology and Nephrology, Charity Hospital of New Orleans, New Orleans, Louisiana, 1980-Present

Consulting Staff, Cardiology and Nephrology, Hood Memorial Hospital, Amite, Louisiana, 1983-1988

Consulting Staff, Cardiology and Nephrology,  Seventh Ward Hospital, Hammond, Louisiana, 1983-1988

Active Staff, Cardiology and Nephrology, Tulane Medical Center Hospital,  New Orleans, Louisiana, 1983-Present

Consulting Staff, Cardiology and Nephrology, Westpark Hospital, Hammond, Louisiana, 1984-1989

Active Staff, Cardiology, Montelepre Memorial Hospital, New Orleans, Louisiana, 1984-Present

Active Staff, Internal Medicine, Cardiology, and Nephrology, Kenner Regional Medical Center, Kenner, Louisiana, 1985-Present

Active Staff, Cardiology and Nephrology, Mercy Hospital, New Orleans, Louisiana, 1985-Present

Active staff, Cardiology and Nephrology, Elmwood Medical Center, Jefferson, Louisiana, 1985-Present

Associate Staff, Cardiology, University Hospital, New Orleans, Louisiana, 1986-1988

Active Staff, University Hospital, New Orleans, Louisiana, 1988-Present

Active Staff, Doctor's Hospital of Jefferson, Metairie, Louisiana, 1993-Present

Active Staff, St. Charles General Hospital, New Orleans, Louisiana, 1994-Present

Active Staff, Touro Infirmary, New Orleans, Louisiana, 1994-Present

Active Staff, Memorial Medical Center, New Orleans, Louisiana, 1985-Present

Active Staff, Lakeside Hospital, Metairie, Louisiana, 1997-Present

PROFESSIONAL:

Director, Electrophysiology Laboratory, Tulane University School of Medicine, 1983-1986

Research Investigator, Clinical Pharmacology,  Tulane University School of Medicine

Director, Cardiology Department, Elmwood Medical Center, Jefferson, Louisiana, 1987-1989

Director, Intensive Care Unit, Elmwood Medical Center, Jefferson,  Louisiana, 1987-1989

Director, Clinical Laboratory, Canal Street Cardiology Associates, New Orleans,  Louisiana, 1993-Present

PROFESSIONAL SOCIETIES

Fellow, American College of Cardiology

Fellow, American College of Chest Physicians

International Society of Nephrology

American College of Physicians

American Federation of Clinical Research

American Heart Association

American Society of Critical Care

American Society of Nephrology

National Medical Association for Internal Medicine

American Medical Association

Tennessee Medical Association

Knoxville Medical Association

RESEARCH PARTICIPATION:

INVESTIGATOR
Louisiana Cardiovascular Research Center
2820 Canal Street
New Orleans, LA  70119
1985- Present

INVESTIGATOR
New Orleans Center for Clinical Research
2820 Canal Street
New Orleans, LA  70119
1994- Present

INVESTIGATOR
Renal Dynamics
2820 Canal Street
New Orleans, LA  70119
1992-Present

INVESTIGATOR
East Tennessee Clinical Research Center
3105 Alcoa Highway, Suite J
Knoxville TN  37920
1993-Present

SUB-INVESTIGATOR
New Tazewell Family Practice
309 Broad Street
New Tazewell, TN 37825

PUBLICATIONS

Smith, W.B., Clifton, G. and Wallin, J.D.: Labetalol in Accelerated Hypertensive Patients; Clinical Research; December, 1982

Wallin, J.D., Smith, W.B., Clifton, G. and O'Neill, J.: Antihypertensive Effectiveness of I.V. Labetalol; Hypertension; July, 1983

Graybar, G., Adler, E., Smith, W.B. and Puyau, F.: Knotting of Swan Ganz Catheters; Chest; August, 1983

Smith, W.B., Ahmad, S., Garland, W.T., Phillips, J.: Reliable M-Mode Diagnosis of Mitral Regurge Following Commissurotomy of Mitral Valve Stenosis; Clinical Research; December, 1983

Vacek, J., Smith, W.B., Ahmad, S., Garland, W.T. and Phillips, J.H.: Cardiac Electrophysiology; Practical Cardiology; 1984

Letora, J.J.L., Smith, W.B., George, W.J., Arvind, B.R., Solomito, J.A., Pinski, W.W., Weinstein, E.W., Wang, T. and Phillips, J.H.: Monitoring, Aminadarone, and Reverse T3 Levels in Patients with Refractory Arrhythmias; Clinical Pharmacology; 1985

Smith, W.B., and Abell, M.M.:  Low Dose Enoximone in Chronic Congestive Heart Failure; Clinical Research ; January, 1990.

Anderson, J.L.; Sorenson, S.G.; Moreno, F.L.; Hackworthy, R.A.; Browne, K.F.; Dale, H.T.; Leya, F.; Dangoisse, V.; Eckerson, H.W.; Marder, V.J.; and Smith, W.B.: Multicenter Patency Trial of Intravenous Anistreplase Compared with Streptokinase in Acute Myocardial Infarction; Circulation; Vol. 83, No. 1; January, 1991

Smith, W.B.: Evolving Therapies of Congestive Heart Failure, ACP , March 1993.

Sharma, S..  Eni, J., Iteld, B., Smith, W.B., Graf, R., Young, J., Nademanee, K., Rayburn, R., Coulter, L., Killebrew, K., Kingry, C., Edwards, J., Deitchman, D.: Sustained Hemodynamic Improvement Following Chronic Fosinopril Therapy in Patients with Heart Failure, ACC November 1993.

Germino, F. W., Lastra, J., Pool, P., Punzi, H., Spinowitz, B., Smith, W.B., Wallace, S., Willett, M., Mills, D., de Silva, J., Cryers, D.: Evaluation of the Cough Profile of Fosinopril in Hypertensive Patients With Ace Inhibitor-Associated Cough-a Pilot Study.

Smith, W.B., DeAbate, A.C., Gollub, S.B., Tonkon, M.J., Grossman, W.J., Sharma, S.C., Goldenberg, I.F., Carley, J.E., Packer, M.: Beneficial Long-Term Hemodynamic and Clinical Effects of Amlodipine in Chronic Heart Failure: Results of a Multicenter Randomized, Double-Blind, Placebo Controlled, Dose Ranging Study, AHA November 1994.

Vargo, D., Kramer, W., Black, P.K., Serpas, T., Brater, D.C.: Bioavailability, Pharmacokinetics and Pharmacodynamics of Torsemide and Furosemide in Patients with Congestive Heart Failure. (1994)

Vargo, D., Gramer, W.G., Grenne, P.K., Smith, W.B., Brater, C.: The Pharmacodynamics of Torsemide in Patients with Congestive Heart Failure. (1993)

Whelton, A., Smith, W.B., Wallin, J.D., Hak, L.J., McLean, B., Goldstein, R.J.: Long-term treatment with Oral Torsemide and its Effect on Body Weight and Fluid Balance in Patients with Chronic Renal Insufficiency. (1996) 

Kramer, W.G., Smith, W.B., Ferguson, J., Serpas, T., Grant, III, A.G., Black, P.K., Brater, D.C.:  Pharmacodynamics of Torsemide Administered as an Intravenous Injection and as a Continuous Infusion to Patients with Congestive Heart Failure (The Journal of Clinical Pharmacology, March 1996)

Packer, M., O'Connor, C.M., Ghali, J.K., Pressler, M.L., Carson, P.E., Belkin, R.N., Miller, A.B., Neuberg, G.W., Frid, D., Wertheimer, J., Cropp, A.B., Demets, D.L., Smith, W.B.: Effect of Amlodipine on Morbidity and Mortality in Severe Chronic Heart Failure (The New England Journal of Medicine, October 1996)

Ma, A., Garland, W.T., Smith, W.B., Skettino, S., Navarro, M., Chan, A.Q., Anderson, B., Messinna, T., Cooke, J.P.:  A Double-Blind, Placebo-Controlled Trial of Ranolazine, A Novel Agent for the Treatment of Intermittent Claudication (The Journal of the American College of Cardiology)

Badalamenti, J., Abboud, H., Lindberg, J., Smith, W.B.: Safety and Efficacy of 19-nor (19-nor-1·, 25-dihydroxyvitamin D2) in Hemodialysis Patients: Results of a Double-Blind, Placebo-Controlled, Multicenter Trial (1997)

Havranek, E.P., Ignatius, T., Smith, W.B., Ponce, G., Bilsker, M., Munger, M., Lyver, S., Aarons, D., Graves, T., Wolf R.A.: Dose-Related Beneficial Long-Term Hemodynamic and Clinical Effects of Irbesartan in Heart Failure (The Journal of the American College of Cardiology 1998).

Lacourcičre, Y., Pool, J.L., Svetkey, L., Gradman, A.H., Larochelle, P., de Champlain, J., Smith, W.B.:  A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial of Four Doses of Tasosartan In Patients with Essential Hypertension

Frishman, W.H., Bittar, N., Glasser, S., Habib, G., Smith, W.B., Pordy, R.:  Additional Anti-Anginal and Anti-Ischemic Efficacy of Mibefradil in Patients Concomitantly Treated with Long-Acting Nitrates for Chronic Stable Angina (Clinical Cardiology)

Udelson, J.E., DeAbate, A., Berk, M., Neuberg, G., Packer M., Vijay, N., Gorwitt, J., Smith, W.B., Kukin, M.L., LeJemtel, T., Levine, T.B., Konstam, M.A., the Amlodipine Exercise Trial Investigators: Effects of Amlodipine on Exercise Tolerance, Quality of Life, and Left Ventricular Function in Patients with Heart Failure Due to Left Ventricular Systolic Dysfunction (Journal of the American College of Cardiology)

Besarab, A., Bolton, W.K., Browne, J.K., Egrie, J.C., Nissenson, A.R., Okamoto, D.M., Schwab, S.J., Goodkin, D.A., The Effects of Normal as Compared with Low Hematocrit Values in Patients with Cardiac Disease who are Receiving Hemodialysis and Epoetin ( The New England Journal of Medicine)

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